Nuspojave Kofeina: 17 Mogućih Načina Kako Višak Kofeina Može Naštetiti

2024 Autor: Cecilia Ryder | [email protected]. Zadnja promjena: 2023-12-17 14:20

Kofein se širom svijeta konzumira zbog svojih stimulativnih svojstava. Međutim, čini se da višak unosa kofeina (posebno kave) nanosi veću štetu. Studije pokazuju da kofein može kod nekih osoba izazvati anksioznost i poremećaje spavanja (1).

Kofein može izazvati ovisnost i ponekad može izazvati štetne učinke čak i u dozama koje se smatraju sigurnima. U ovom postu nabrojali smo najčešće nuspojave od previše kofeina. Budite svjesni toga prije nego što uzmete sljedeću šalicu.

Sadržaj

• Kofein - Ukratko
• Kako kofein utječe na naše tijelo?
• Nuspojave kofeina
• Simptomi povlačenja kofeina
• Preporučena doza kofeina

Kofein - Ukratko

Kofein je poznat kao trenutni pojačivač energije. Pomaže ljudima u borbi protiv pospanosti. Ipak postoji mnogo kontroverzi oko njegove doze i učinkovitosti.

Kofein, znanstveno poznat kao metil teobromin, alkaloid je. Ova se prirodna tvar nalazi u mnogim biljkama, uključujući zrna kave, čaj, kolače i mahune kakaa. Ovaj alkaloid važan je dio komercijalne platforme, a njegov umjetni oblik široko se koristi u proizvodnji ljekarničkih lijekova, pića, čokolade i infuzija kave.

Prema istraživanjima, kofein je psihostimulans koji se najviše konzumira na svijetu (2). To pokazuje kako je vjerojatno da će se i prekomjerno konzumirati.

Kako kofein utječe na naše tijelo?

Kako je topiv u vodi, kofein se lako apsorbira u našem sustavu. Začas dolazi do našeg krvotoka, počevši od želuca do mozga. Ima li nuspojava? Pročitajte dalje.

Nuspojave kofeina

1. Može izazvati napade tjeskobe
2. Može uzrokovati poremećaje želuca
3. Može uzrokovati nesanicu
4. Može uzrokovati pobačaj
5. Može povećati razinu krvnog tlaka
6. Može izazvati menstrualne probleme
7. Može povećati rizik od urinarne inkontinencije
8. Moglo bi uzrokovati debljanje
9. Može uzrokovati halucinacije
10. Može povećati šanse za osteoporozu
11. Svibanj ometa proizvodnju estrogena
12. Može povećati vjerojatnost nastanka cista na dojkama
13. Možda neće biti dobro za osobe s dijabetesom tipa 2
14. Može inhibirati stvaranje kolagena u koži
15. Može oštetiti oporavak sluha
16. Svibanj pokreće akne
17. Može uzrokovati alergije

Njegova ovisnost čini kofein velikim rizikom, posebno među tinejdžerima i odraslima. Nuspojave kofeina s velikim iskustvom uključuju dehidraciju, prekomjerno stvaranje mokraće što dovodi do dehidracije, želučanih poremećaja, mučnine, povišenog krvnog tlaka, depresije, nemira, povećanog broja otkucaja srca koji dovodi do smrti, pretilosti, povećane tjelesne težine i vrućice.

Pročitajte kako biste dobili detaljnu sliku nuspojava kofeina:

1. Može izazvati napade tjeskobe

Pretjerani unos kofeina može dovesti do ozbiljnog slučaja tjeskobe. Studije rađene na srednjoškolskoj djeci pokazale su da bi visok unos kofeina mogao biti povezan s osjećajem tjeskobe i stresa (3).

Poznato je da osoba s tjeskobom osjeća nervozu i nemir, čak i pod normalnim uvjetima. Kofein pogoršava takva stanja (3). Stoga treba biti vrlo oprezan ako imaju te simptome.

Metoda prevencije

Ljudi s anksioznim poremećajima trebaju se posavjetovati sa svojim liječnicima prije nego što se odluče za kofein. To može isključiti šanse za interakcije s lijekovima.

2. Može uzrokovati poremećaje želuca

Kiseline prisutne u kofeinu potiču želudac da proizvodi više kiseline. Čini se da kofein (kava) potiče gastroezofagealni refluks (4). Anegdotski dokazi sugeriraju da previše kofeina također može dovesti do želučanih poremećaja poput mučnine, grčeva, proljeva i nadutosti.

Metoda prevencije

Ako imate slab želudac, ograničite dnevnu dozu kofeina na dvije šalice (maksimalno).

3. Može uzrokovati nesanicu

Nesanica je poremećaj spavanja u kojem osoba teško pada ili spava. To je simptom odvikavanja, koji se kombinira s drugim fizičkim problemima, poput povećanog umora i glavobolje. Ovo je čest znak među onima koji konzumiraju puno kofeina.

Takvi bi ljudi doživjeli nesanicu i razdražljivost kad bi se povukli iz kofeina. Iako određene studije nisu pronašle veće učinke, unos kofeina neposredno prije spavanja povezan je s nesanicom (5).

Metoda prevencije

Najlakši način za suzbijanje nesanice je izbjegavanje kofeina prije spavanja. Smanjenje broja šalica dnevno također može pomoći.

4. Može uzrokovati pobačaj

Trudnice bi trebale biti oprezne s kofeinom jer pretjerani unos može dovesti do pobačaja i drugih komplikacija prije porođaja (6).

Caffeine is water-soluble and easily crosses the placenta through the bloodstream. As it is a stimulant, it can cause a rapid increase in the heart rate and metabolism of the fetus. One of the side effects of too much caffeine includes delayed fetal growth (7).

Breastfeeding mothers should not consume more than two cups of coffee per day as it affects the baby directly by causing physical irritability. It may also affect iron status in the infant (8).

Prevention Method

Consult your family physician before you decide to take caffeine regularly. Under any circumstances, would-be mothers should not take more than 200 mg of caffeine in a day.

5. May Increase Blood Pressure Levels

People who have hypertension should be cautious about the amount of caffeine they consume on a daily basis.

Caffeine is known to spike your blood pressure for a short time (9). While there are no long-term effects of caffeine, some believe it may worsen the condition in people with irregular heart rhythms. On the other hand, certain studies state that the intake of coffee is not linked to hypertension (10). Hence, more research is needed to establish a connection.

Caffeine is also associated with a heart attack in young adults. According to a study, young adults with mild hypertension who consume more than four cups of coffee in a day are four times more vulnerable to heart attack than those who consume two cups or less (11).

Prevention Method

If you have hypertension or cardiovascular problems, it is better to seek a medical opinion before including caffeine in your daily routine.

6. May Induce Menstrual Problems

While a hot cup of coffee feels great during those days, excessive intake of caffeine can meddle with your menstrual cycle. It can cause period delays, excessive flow, and prolonged cramps.

Caffeine also increases the chance of vasomotor in menopausal women.

According to a study published in The Journal of The North American Menopause Society, menopausal women who are dependent on caffeine have a greater chance of displaying vasomotor symptoms (12).

Prevention Method

Quantity is key. You should always measure what you consume, whether it is caffeine or not. Consulting a doctor is also an important step, especially if you have menstrual problems.

7. May Increase The Risk Of Urinary Incontinence

Caffeine increases the chances of urinary incontinence in women (13). It is a bladder disorder in which the person loses control of the bladder. It results in the sudden leakage of urine whenever the person laughs, coughs, or sneezes.

Prevention Method

Avoid consuming more than two cups of caffeine in a day.

8. Might Cause Weight Gain

Caffeine may induce stress. Animal studies show that stress can lead to obesity (14). However, there is no direct research stating that caffeine can lead to weight gain and long-term obesity.

Some believe that caffeine brings up the levels of stress hormones, which results in increased hunger pangs. This is not proven by research, though.

Prevention Method

Coffee is great. But making it a habit can add extra kilos to your body. Make it a point to have no more than two-three cups of caffeine in a day, and that includes coffee, cola, chocolate, and tea.

9. May Cause Hallucinations

It is true that caffeine can make you high. If you go overboard, you may experience confusion and hallucinations. These effects were more pronounced in those taking more than seven cups of coffee (more than 300 mg of caffeine in a day) (15). In some cases, this has even led to death due to convulsions (16).

Prevention Method

If you feel you are getting addicted to caffeine, start cutting down your daily consumption slowly.

10. May Increase The Chances Of Osteoporosis

Consuming caffeine in large quantities may also increase the risk of osteoporosis. This effect was found to be true in elderly women, whose calcium performance was already impaired (17). It interferes with the absorption of calcium, resulting in bone thinning (osteoporosis), especially in older women whose intake of calcium is below the recommended intake (18).

Overconsumption of caffeine may also cause achy muscles and twitches, though more research is needed to understand this aspect.

Prevention Method

Avoid caffeine if you have calcium deficiency, as it may worsen the condition.

11. May Interfere With Estrogen Production

Caffeine is known to interfere with estrogen production and metabolism. While it increased estrogen production in Asians, it decreased the levels in white females (19).

Some believe that caffeine can reduce a woman’s chances of getting pregnant (the higher the caffeine dependency, the greater the risk), though this has not been proven.

It also is believed that caffeine can have strong effects that may complicate pregnancy. Since research is lacking, we suggest that women who look forward to conceiving consult their doctor before taking caffeine.

Prevention Method

Consult your doctor for the recommended safe dosage of caffeine.

12. Can Increase The Chance Of Breast Tissue Cysts

According to a published study, women who consume more than 500 mg of caffeine per day have twice more chances of developing breast tissue cysts than those who take 31-250 mg of caffeine (20).

Prevention Method

Limit your caffeine intake.

13. May Not Be Good For Individuals With Type 2 Diabetes

If you have type 2 diabetes, you may want to consider limiting your caffeine intake. It may impair glucose metabolism, increasing the risk of diabetes complications (21).

Prevention Method

Consult your physician and get your daily caffeine limit defined.

14. Can Inhibit Collagen Production In The Skin

Caffeine was found to reduce collagen production in human skin (22).

Prevention Method

This problem could be easily prevented by limiting your caffeine dose.

15. May Impair Hearing Loss Recovery

According to a study conducted on guinea pigs, caffeine may also delay the recovery rate of noise-induced hearing loss (23). The same correlation is believed to be observed in humans as well.

Prevention Method

The ideal solution is not to consume more than 400 mg of caffeine in a day.

Insufficient Evidence For The Following

16. May Trigger Acne

Having numerous cups of coffee in a day can also cause acne. Caffeine magnifies the body’s stress levels by boosting stress hormones, which is one of the main reasons for breakouts. Caffeine can also throw your body off balance, causing stress and eventually breakouts.

Prevention Method

If you love your skin and are quite vulnerable to acne breakouts, limit your caffeine intake.

17. May Cause Allergies

Caffeine allergy is highly uncommon, but some people might develop oversensitivity to it. This may cause allergic symptoms, like rashes, hives, and pain.

Prevention Method

If you experience such reactions, it is better to quit caffeine. Seek a doctor’s advice if the problem persists.

Some of the side effects could be quite uncomfortable. But does this mean you need totally abstain from caffeine? Well, doing that too early may lead to caffeine withdrawal, especially if you are used to consuming caffeine on a regular basis.

Symptoms Of Caffeine Withdrawal

According to research, more than 68 million Americans are caffeine-dependent.

But why do we get addicted to caffeine?

Caffeine is a smart drug. It suppresses adenosine, a chemical produced by the brain that relaxes our body. It leads to a tense surge of energy in our system. This, in turn, forces our brain to demand increased levels of caffeine to stimulate the same reaction. Thus, caffeine dependency is created. These are the caffeine side effects on the brain.

People who try to get off caffeine experience a lot of withdrawal symptoms. These symptoms are generally mild but can also be fatal for those who are highly accustomed to caffeine.

The general short-term withdrawal symptoms include (24):

• Headache
• Nausea
• Irritability
• Vomiting
• Grogginess
• Lethargy
• Muscle pain
• Depression
• Lack of concentration

Recommended Dosage Of Caffeine

Caffeine, with its taste and neuropsychiatric effects, has claimed a prominent place in our lives. Whether it is in chocolates or your morning beverage, it is almost impossible to avoid it. But there’s an important question we need to consider – how much of caffeine is too much?

Caffeine is a drug. Just like other allopathic drugs, caffeine can also affect people differently. Always remember that any pre-existing medical condition can add to the negative effects of caffeine. Thus, knowing our body condition, medical history, and daily intake is important. In fact, half the troubles associated with this drug can be diminished by keeping a tab on the quantity consumed daily.

What is the safe limit for caffeine?

A healthy adult can consume up to 400 mg (about 4 cups of coffee, or 10 cans of aerated caffeinated drinks) of caffeine daily without worrying about the side effects (24). However, this upper limit is highly dependent on your present health condition and other medications you are on.

Children under the age of five should avoid caffeine. Teenagers and young adults should not go for more than 100 mg of caffeine daily.

Conclusion

Though caffeine is generally considered safe for most people, too much of it can cause harm. It is important you stick to just a cup or two of coffee a day. However, pregnant and breastfeeding women are recommended to avoid caffeine.

If you are on any medications or have any specific health condition, we suggest you speak to your health care provider before you start consuming caffeine.

Expert’s Answers For Readers’ Questions

Does caffeine cause dehydration and dry mouths?

Caffeine is a natural diuretic. Some theories suggest that caffeine causes too much fluid to leave the system, resulting in dehydration and a dry mouth. Some also believe that having caffeine is not a good idea while working out as it can cause excessive dehydration. However, research is limited.

In fact, one study states that there could be no link between caffeine intake and dehydration or dry mouth (25).

Does caffeine increase the risk of gout?

Research is limited here. Conversely, some research suggests that long-term caffeine intake may reduce the risk of gout (26). To be on the safe side, if you have gout, please consult your doctor before consuming caffeine.

What are the different ways to reduce caffeine intake?

One should never quit caffeine abruptly. It may lead to severe withdrawal symptoms, especially if you are habituated to caffeine.

A better solution is to go for a step-by-step reduction method. Begin by cutting down on the number of cups you take in a day. Continue this for a few months until you are sure you won’t cheat. Then, start replacing this high-caffeine beverage with something healthier, like green or white tea and organic fruit juice. Keep your physician in the loop at all times.

Can we take supplements along with caffeine?

You are allowed to take certain supplements along with caffeine, especially those that are known to help cleanse the colon, stimulate digestive enzymes, and rehydrate cells. However, one must avoid herbs and supplements that are known to increase the risk of bleeding. Do consult your doctor before going for drugs and supplements as your medical history may aggravate the problem.

How much caffeine is found in chocolates and beverages?

Coffee is known to contain the maximum amount of caffeine. The quantity of caffeine, however, is highly dependent on the brewing method, the strength of the brew, type of coffee bean, and the cup size. A typical 250 ml cup of black coffee contains about 85 mg of caffeine. A single espresso shot has about 63 mg caffeine, while one cup of decaf coffee contains about 3 mg caffeine.

On the other hand, an 8-ounce can of red bull contains about 78-80 mg of caffeine. A cup of green tea is known to contain 20-45 mg of caffeine. Cola contains about 30-48 mg of caffeine per can.

Like coffee, the caffeine content in chocolates is also highly dependent on its type. A bar of milk chocolate contains about 1.4 mg of caffeine, which can go as high as 70 mg for a typical dark chocolate bar.

25 sources

Stylecraze ima stroge smjernice za izvor i oslanja se na recenzirane studije, akademske istraživačke institucije i medicinska udruženja. Izbjegavamo koristiti tercijarne reference. Možete pročitati više o tome kako osiguravamo da je naš sadržaj točan i aktualan čitajući našu uredničku politiku.

• Kofein i središnji živčani sustav: mehanizmi djelovanja, biokemijski, metabolički i psihostimulacijski učinci, Recenzije istraživanja mozga, Američka nacionalna medicinska knjižnica, Nacionalni institut za zdravlje.

  www.ncbi.nlm.nih.gov/pubmed/1356551

• Kofein u prehrani: Potrošnja i smjernice na razini države, hranjive tvari, Američka nacionalna medicinska knjižnica, Nacionalni zavodi za zdravlje.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC6266969/

• Caffeine consumption and self-assessed stress, anxiety, and depression in secondary school children, Journal of Psychopharmacology, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC4668773/

• Coffee and gastrointestinal function: facts and fiction. A review, Scandinavian journal of gastroenterology, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/10499460

• A Study of Caffeine Consumption and Symptoms: Indigestion, Palpitations, Tremor, Headache and Insomnia, International Journal of Epidemiology, US National Library of Medicine, National Institutes of Health.

  watermark.silverchair.com/14-2-239.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAm4wggJqBgkqhkiG9w0BBwagggJbMIICVwIBADCCAlAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMW-Kp_NVwxXt_BtCFAgEQgIICIRp371sJVr1s33Bqq95II4hDxzp3Xt732Rv-nAng6F9tj5CPi9YZYR_-epzPEVLrPuYGpICRUWj68c9299BZdu-M0s1u9eI0EiCS0lPhXThGbn0vRHpwtEmaEO2Ea0ZXzuRU_6pEk6yds1-9SebtRUtbizKxIQZYMTyqre6sVmOfbSdyrx0uJY_H0MTx63YfWE4hrcAIaj47qWvuRUAOfKkd1-gjPwzy1IXqxkPp_B19UI98uHNvTZbTgp5cjZDeThkqdd6flgJcYIvQBq2TCXamnMuAzgNBtMFdMiSzTLtTFfhDv7cEJTIgdZv6Jt6ME7osihRPlo7P1FLDnH-McaSboF9bz05nygSAXEWRDyqCku6_XujSfb_iMgfbr9GQzs3s7rV4RvbnHKW7xzPGUEGV0a3KmP3By5Zskibq5BvWWW9eQfPAXwcOxDFwAPZKvVpgVJwdfK3UpYKTGDcM_qIbUAlw6bcpn2Z7TMlcpKm9YhEeGym4_ryG42Ut4XRmxULXy9NpJ7vDXoKDhlkKIkzd2xEO5oMFCCe-yDNWOSHR2y5NxSg02ETmgoR32GW8deCKiaV2vcsG33kr-pjlSmw2nihvlD8APSFsqXbe64JqgqXdXckWH0-5-zPS6i1LSed_aa6u71F18CKruvdBQ8l4uEld2gys8i6azft4sOu5WdX0XKUiTDtfvhjNxUsouUFYfaYtNKqFjXL3LQPUpBdX

• Couples’ pre-pregnancy caffeine consumption linked to miscarriage risk, National Institutes of Health.

  www.nih.gov/news-events/news-releases/couples-pre-pregnancy-caffeine-consumption-linked-miscarriage-risk

• Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study, BMJ, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC2577203/

• Infant Outcomes, Nutrition During Lactation, National Center for Biotechnology Information.

  www.ncbi.nlm.nih.gov/books/NBK235581/

• Are You Wrong About Your Blood Pressure?, Centers for Disease Control and Prevention.

  www.cdc.gov/features/blood-pressure-tips/index.html

• Habitual coffee consumption and blood pressure: an epidemiological perspective, Vascular Health and Risk Management, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/19183744

• Coffee linked with increased cardiovascular risk in young adults with mild hypertension, European Society of Cardiology.

  www.escardio.org/The-ESC/Press-Office/Press-releases/Coffee-linked-with-increased-cardiovascular-risk-in-young-adults-with-mild-hypertension

• Menopause and Hormone Replacement, National Center for Biotechnology Information.

  www.ncbi.nlm.nih.gov/books/NBK279050/

• CAFFEINE AND URINARY INCONTINENCE IN US WOMEN, International urogynecology journal, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC3505252/

• Effects of Chronic Social Stress on Obesity, Current obesity reports, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC3428710/

• Energy Drinks and the Neurophysiological Impact of Caffeine, Frontiers in Neuroscience, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC3198027/

• Fatal caffeine overdose: two case reports, Forensic Science International, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/15935584

• Is caffeine consumption a risk factor for osteoporosis?, Journal of Bone and Mineral Research, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/1609631

• Caffeine, urinary calcium, calcium metabolism and bone, The Journal of Nutrition, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/8360789

• NIH Study shows caffeine consumption linked to estrogen changes, National Institutes of Health.

  www.nih.gov/news-events/news-releases/nih-study-shows-caffeine-consumption-linked-estrogen-changes

• Caffeine consumption and fibrocystic breast disease: a case-control epidemiologic study, Journal of the National Cancer Institute, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/6585579

• Caffeine Impairs Glucose Metabolism in Type 2 Diabetes, American Diabetes Association.

  care.diabetesjournals.org/content/27/8/2047

• Influence of caffeine and hyaluronic acid on collagen biosynthesis in human skin fibroblasts, Drug Design, Development and Therapy, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pmc/articles/PMC4206198/

• Association of Caffeine and Hearing Recovery After Acoustic Overstimulation Events in a Guinea Pig Model, JAMA Network.

  jamanetwork.com/journals/jamaotolaryngology/fullarticle/2498969

• Caffeine Withdrawal, National Center for Biotechnology Information.

  www.ncbi.nlm.nih.gov/books/NBK430790/

• Caffeine ingestion and fluid balance: a review, Journal of Human Nutrition and Dietetics, US National Library of Medicine, National Institutes of Health.

  www.ncbi.nlm.nih.gov/pubmed/19774754